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Montag, 10. Dezember 2018

International Symposium on Bone Regeneration

Datum: June 11 - 13, 2015Ort: Berlin, Germany

Aims

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ISBR

International Symposium

on Bone Regeneration

– Crosstalk between progenitor cells, immune cells and the extracellular matrix –

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Illustrated by Paul Stabe

 


Bone is one of the few tissues in the body that has the general capability

of scar less, endogenous regeneration resulting in complete functional

and structural reconstitution.

Thus, bone is an ideal model system to evaluate the effect of stress factors or constraints of healing on a cellular and tissue level. However, apparently a shift occurs with aging in our endogenous regenerative capacity and the number of patients with metabolic and musculoskeletal diseases increase together with the aging population in industrialized countries. Regenerative medicine aims at completely restoring tissue structure and function by supporting endogenous regeneration.


Basic knowledge about molecules of the extracellular matrix, the immune response and the function of stem and progenitor cells during regeneration has cumulated over the last decade.

Nevertheless, the interconnectivity of different aspects of the healing cascade is often underestimated in research studies. A prerequisite for the successful implementation of regenerative medicine is an understanding of the complex mechanisms interacting during regeneration.

 

By initiating discussion and interaction between basic disciplines involved in investigating the regeneration of musculoskeletal tissues, we aim to strengthen exchange between the disciplines that are essential for initiating new concepts specifically for those patients at need for new therapies. This symposium will try to combine different angles of regeneration, offering the possibility to discuss with specialists form different regenerative fields the importance of the interdependency of different tissues and cellular systems in regeneration, thus opening the possibility to begin an interaction between immunological, stem cell based, mechanical and metabolic aspects of regeneration.